Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Tuesday, February 22, 2005

Epistasis in RNA Viruses

Several recent papers document epistasis in RNA viruses. See, for example:

Sanjuan R, Moya A, Elena SF. The contribution of epistasis to the architecture of fitness in an RNA virus. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15376-9. [PubMed]

Bonhoeffer S, Chappey C, Parkin NT, Whitcomb JM, Petropoulos CJ. Evidence for positive epistasis in HIV-1. Science. 2004 Nov 26;306(5701):1547-50. [PubMed]

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