Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Saturday, July 09, 2005

Leo Breiman died Tuesday, July 5th

Leo Breiman, professor emeritus of statistics at UC Berkeley, died on Tuesday, July 5th. Dr. Breiman is best known for his work on classification and regression trees (CART) which are applicable to genetic analysis. The UC Berkeley press release can be read here.

The following paper illustrates the use of classification trees for identifying gene-gene interactions:

Bureau et al. Identifying SNPs predictive of phenotype using random forests. Genet Epidemiol. 2005 Feb;28(2):171-82. [PubMed]

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