Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Thursday, September 18, 2008

MDR 2.0 alpha released

Version 2.0 alpha of our multifactor dimensionality reduction (MDR) software package has been released on Sourceforge.net. You can download it from here. More information about MDR can be found here. An MDR tutorial can be found in a 5-part series of posts on this blog from November to December of 2006.

This newest version of MDR includes a simple univariate estimation of distribution algorithm (EDA) that uses expert knowledge to probabilistically select SNPs from a genome-wide association study for MDR modeling. See my recent June 2008 post for more information.

This is an alpha version which means there might still be bugs or other problems despite our rigorous testing. Please keep this mind as you use it and email us feedback.

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