Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Tuesday, February 17, 2009

New evaluation measures for multifactor dimensionality reduction (MDR)

There are two recent papers that propose alternatives to accuracy as a measure of the quality of MDR models. See:

Namkung J, Kim K, Yi S, Chung W, Kwon MS, Park T. New evaluation measures for multifactor dimensionality reduction classifiers in gene-gene interaction analysis. Bioinformatics. 2009 Feb 1;25(3):338-45. [PubMed]

Bush WS, Edwards TL, Dudek SM, McKinney BA, Ritchie MD. Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction. BMC Bioinformatics. 2008 May 16;9:238. [PubMed]

Which of these would users like to see added to our open-source MDR software package? Let me know.

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