Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Wednesday, April 06, 2005

Gene-Environment Interactions

A new review paper by David Hunter focuses on gene-environment interactions in human disease:

Hunter DJ. Gene-environment interactions in human diseases. Nat Rev Genet. 2005 Apr;6(4):287-298. [PubMed]

No discussion about gene-environment interactions is complete without covering reaction norms. For more information on reaction norms and phenotypic plasticity, I highly recommend the following books:

Schlichting CD, Pigliucci M. Phenotypic Evolution: A Rection Norm Perspective. Sinauer (1998). [Amazon.com]

Pigliucci M. Phenotypic Plasticity: Beyond Nature and Nurture. Johns Hopkins University Press(2001). [Amazon.com]

Pigliucci M. Phenotypic Integration: Studying the Ecology and Evolution of Complex Phenotypes. Oxford University Press(2004). [Amazon.com]

See also: http://www.genotype-environment.org/

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