Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Tuesday, May 03, 2005

MDR Data Tool

The Dartmouth CGL is happy to announce the availability of a Data Tool module for our multifactor dimensonality reduction (MDR) software package. The Data Tool makes it possible to convert between several different data formats, impute missing genotypes using a simple model, and resample the data to create balanced case/control ratios. The Data Tool module joins the Analysis module and the Permutation Testing module to complete the open-source MDR software package. All three modules will be continuously updated with new features. Please check back often for updates.

The MDR Data Tool can be downloaded from here.

Information about the MDR method and algorithm can be found online here.

** NOTE ** We have changed the basic MDR data format for all three modules. The new format requires the class variable (i.e. case/control status) to be in the last column. Also, the new format accepts variable names/headers in the first row of each column. This new data format is more consistent with how most research datasets are formatted. The Data Tool will read the old MDR format and save files in the new format. The data tool will also read and save files in Weka ARFF format.

Please let us know if there are additional features you would like to see in any of the three MDR modules.

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