Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Saturday, May 07, 2005

Hardy-Weinberg Equilibrium

Tests of departure from Hardy-Weinberg equilibrium are often misunderstood and misused. Everyone doing genetic studies in human populations should read the following paper:

Wittke-Thompson JK, Pluzhnikov A, Cox NJ. Rational Inferences about Departures from Hardy-Weinberg Equilibrium. Am J Hum Genet. 2005 Jun;76(6):967-86. [PubMed]

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