Epistasis Blog

From the Computational Genetics Laboratory at the University of Pennsylvania (www.epistasis.org)

Monday, August 22, 2005

Classic paper on interactions

The following is a classic paper on the concept of interaction from an epidemiology and public health perspective. I highly recommend it for those new to the area. Rothman specifically discusses statistical vs. biological interaction.

Rothman KJ, Greenland S, Walker AM. Concepts of interaction. Am J Epidemiol. 1980 Oct;112(4):467-70. [PubMed]

Here is another one of my favorite papers by Dr. Rothman. Those of you that struggle with the appropriate correction for multiple testing should read this.

Rothman KJ. No adjustments are needed for multiple comparisons. Epidemiology. 1990 Jan;1(1):43-6. [PubMed]

Here is a new paper by Rothman that I have not read yet. Let me know how you like it.

Rothman KJ, Greenland S. Causation and causal inference in epidemiology. Am J Public Health. 2005 Jul;95 Suppl 1:S144-50. [PubMed]

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