Atherosclerosis: from genetic polymorphisms to system genetics.

A new paper by Francois Cambien in Cardiovascular Toxicology reviews the importance of gene-gene and gene-environment interactions in atheroscerosis. A systems-genetics approach is discussed.

Cambien F, Tiret L. Atherosclerosis: from genetic polymorphisms to system genetics. Cardiovasc Toxicol. 2005;5(2):143-52. [PubMed]

Here is another nice review that covers the complexity of cardiovascular disease:

Sing CF, Stengard JH, Kardia SL. Dynamic relationships between the genome and exposures to environments as causes of common human diseases. World Rev Nutr Diet. 2004;93:77-91. [PubMed]